Codon usage optimization in pluripotent embryonic stem cells.

Susanne BornelövTommaso SelmiSophia FladSabine DietmannMichaela Frye

Published in: Genome biology (2019)

We show that GC content influences cell state-specific mRNA levels, and we reveal how translational mechanisms based on tRNA modifications change codon usage in embryonic stem cells.

Keyphrases

embryonic stem cells
single cell
cell therapy
genome wide
gene expression
mesenchymal stem cells
gas chromatography
high resolution