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Functional relevance of genes predicted to be affected by epigenetic alterations in atypical teratoid/rhabdoid tumors.

Isabel TegederKatharina ThielSerap ErkekPascal D JohannJohannes BerlandiVenu ThatikondaMichael C FrühwaldMarcel KoolAstrid JeibmannMartin Hasselblatt
Published in: Journal of neuro-oncology (2018)
These results suggest that a subset of genes affected by differential histone modification in ATRT is involved in the detrimental effects of SMARCB1-deficiency and also relevant in the biology of ATRT.
Keyphrases
  • dna methylation
  • genome wide
  • genome wide identification
  • bioinformatics analysis
  • genome wide analysis
  • replacement therapy
  • transcription factor