Tumor Grade and Mitotic Count Are Prognostic for Dogs with Cutaneous Mast Cell Tumors Treated with Surgery and Adjuvant or Neoadjuvant Vinblastine Chemotherapy.
Kristina AndersonMacKenzie A PellinElizabeth SnyderDawn ClarkePublished in: Veterinary sciences (2024)
Both grading systems and MC were prognostic for survival in this population of dogs, supporting the need for the standard reporting of histopathologic findings. Neoadjuvant chemotherapy can be effective in downsizing cMCTs but does not influence survival. These findings are consistent with previous publications, showing the benefits of a more modern population of patients, surgical treatments, and histopathologic assessments.
Keyphrases
- neoadjuvant chemotherapy
- locally advanced
- lymph node
- rectal cancer
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- minimally invasive
- ejection fraction
- early stage
- sentinel lymph node
- prognostic factors
- free survival
- emergency department
- coronary artery bypass
- cell cycle
- patient reported outcomes
- adverse drug