Dynamins combine mechano-constriction and membrane remodeling to enable two-step mitochondrial fission via a 'snap-through' instability.
Haleh AlimohamadiElizabeth Wei-Chia LuoRena YangShivam GuptaKelsey A NoldenTaraknath MandalR Blake HillGerard C L WongPublished in: bioRxiv : the preprint server for biology (2024)
Dynamin mechano-constriction by assembly and curvature-driven instability by free monomers synergistically drive mitochondrial fission.