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Genetic Analysis of SARS-CoV-2 Variants in Mexico during the First Year of the COVID-19 Pandemic.

Blanca Itzel Taboada-RamírezSelene ZaratePavel IšaCelia BoukadidaJoel Armando Vazquez-PerezJosé Esteban Muñoz-MedinaJosé Ernesto Ramírez-GonzálezAndreu Comas-GarcíaConcepción Grajales-MuñizAlma Rincón-RubioMargarita Matías-FlorentinoAlejandro Sánchez-FloresEdgar Mendieta-CondadoJerome J VerleyenGisela Barrera-BadilloLucía Hernández-RivasFidencio Mejía-NepomucenoJosé Arturo Martínez-OrozcoEduardo Becerril-VargasSusana LópezIrma López-MartínezSantiago Ávila-RíosCarlos F Arias
Published in: Viruses (2021)
During the first year of the SARS-CoV-2 pandemic in Mexico, more than two million people were infected. In this study, we analyzed full genome sequences from 27 February 2020 to 28 February 2021 to characterize the geographical and temporal distribution of SARS-CoV-2 lineages and identify the most common circulating lineages during this period. We defined six different geographical regions with particular dynamics of lineage circulation. The Northeast and Northwest regions were the ones that exhibited the highest lineage diversity, while the Central south and South/Southeast regions presented less diversity with predominance of a certain lineage. Additionally, by late February 2021, lineage B.1.1.519 represented more than 89% of all circulating lineages in the country.
Keyphrases
  • sars cov
  • single cell
  • respiratory syndrome coronavirus
  • cell fate
  • dna methylation