Ketamine as augmentation for the treatment of major depression and suicidal risk in advanced cancer: Case report.

Oscar Rodríguez-Mayoral Rodrigo Pérez-EsparzaGeorgina Domínguez-OcadioSilvia Allende-Pérez

Published in: Palliative & supportive care (2020)

This case report shows ketamine's efficacy as an augmentation agent alongside conventional antidepressant treatment in patients with AC. Moreover, it shows rapid response in suicidal ideation that has not been achieved with treatment as usual. More clinical trials are needed to support the potential benefit and safety of ketamine in patients with AC, MDD, and persisting suicidal ideation.

Keyphrases

case report
clinical trial
major depressive disorder
pain management
depressive symptoms
combination therapy
soft tissue
replacement therapy
sensitive detection
placebo controlled