Correlations between intravoxel incoherent motion-derived fast diffusion and perfusion fraction parameters and VEGF- and MIB-1-positive rates in brain gliomas: an intraoperative MR-navigated, biopsy-based histopathologic study.

Yaru ShengXuefei DangHua ZhangWenting RuiJing WangHaixia ChengTianming QiuYong ZhangYueyue DingZhenwei YaoHaopeng PangHai-Tao Lv

Published in: European radiology (2023)

• Intravoxel incoherent motion-diffusion-weighted imaging (IVIM-DWI)-derived fast diffusion (Dfast) and perfusion fraction (PF) can quantitatively reflect intratumor pVEGF and pMIB-1. • IVIM-DWI-derived Dfast and PF tend to demonstrate better efficacy in evaluating glioma malignancy when an optimized scheme is used. • IVIM-DWI-derived Dfast5000 and PF5000 are promising non-invasive parameters correlating with pVEGF and pMIB-1 in gliomas.

Keyphrases

diffusion weighted imaging
contrast enhanced
diffusion weighted
magnetic resonance imaging
magnetic resonance
computed tomography
high grade
multiple sclerosis
white matter
brain injury
mass spectrometry
subarachnoid hemorrhage
cerebral ischemia
ultrasound guided
blood brain barrier