Login / Signup

Resolution Enhancement in Wide-Field IR Imaging and Time-Domain Spectroscopy Using Dielectric Microspheres.

Dean N EdunClaire E NelmarkArnaldo L Serrano
Published in: The journal of physical chemistry. A (2020)
Wide-field imaging through dielectric microspheres has emerged in recent years as a simple and effective approach for generating super-resolution images at visible wavelengths. We present, to our knowledge, the first demonstration that dielectric microspheres can be used in a wide-field infrared (IR) microscope to enhance the far field resolution. We have observed a substantial improvement in resolution and magnification when images are collected through polystyrene microspheres. In addition, we demonstrate that spectroscopic imaging with a pulse-shaper based femtosecond mid-IR laser system is possible through the dielectric microspheres, which is a promising first step toward applying this technique to ultrafast IR imaging methods such as pump-probe and 2DIR microscopy.
Keyphrases
  • high resolution
  • single molecule
  • molecularly imprinted
  • healthcare
  • optical coherence tomography
  • machine learning
  • convolutional neural network
  • mass spectrometry
  • molecular docking
  • quantum dots