Graptopetalum paraguayense Inhibits Liver Fibrosis by Blocking TGF-β Signaling In Vivo and In Vitro.
Wei-Hsiang HsuSe-Chun LiaoYau-Jan ChyanKai-Wen HuangShih-Lan HsuYi-Chen ChenMa-Li SiuChia-Chuan ChangYuh-Shan ChungChi-Ying F HuangPublished in: International journal of molecular sciences (2019)
These findings indicate that GP/HH-F3 may be a potential therapeutic agent for the treatment of liver fibrosis. The inhibition of TGF-β-mediated fibrogenesis may be a central mechanism by which GP/HH-F3 protects the liver from injury.