Insights into the functional aspects of poly(ADP-ribose) polymerase-1 (PARP-1) in mitochondrial homeostasis in Dictyostelium discoideum.

Ashlesha KadamTina JubinRittwika RoychowdhuryAbhishek GargNishant ParmarSayantani Pramanik PalitRasheedunnisa Begum

Published in: Biology of the cell (2020)

This study would provide new clues on the PARP-1's crucial role in mitochondrial homeostasis, exploring the therapeutic potential of PARP-1 in various mitochondrial diseases.

Keyphrases

dna damage
oxidative stress
dna repair