Augmentation of DNA exonuclease TREX1 in macrophages as a therapy for cardiac ischemic injury.

Ahmed Gamal-Eldin IbrahimAlessandra CiulloKazutaka MiyamotoKe LiaoXaviar M JonesShukuro YamaguchiChang LiAlice RannouAsma NawazAshley MorrisKara TsiCristina H MarbánJamie LeeNancy ManriquezYeojin HongArati Naveen KumarJames F DawkinsRussell G RogersEduardo Marbán

Published in: bioRxiv : the preprint server for biology (2024)

Upregulation of three prime exonuclease, TREX1, in macrophages enhances tissue repair post myocardial infarction.

Keyphrases

left ventricular
heart failure
cell proliferation
single molecule
cell free
signaling pathway
ischemia reperfusion injury
nucleic acid
atrial fibrillation
subarachnoid hemorrhage