Relationship between amyloid and tau levels and its impact on tau spreading.
Vincent DoréNatasha KrishnadasPierrick BourgeatKun HuangShenpeng LiSamantha BurnhamColin L MastersJurgen FrippVictor L VillemagneChristopher C RowePublished in: European journal of nuclear medicine and molecular imaging (2021)
Outside the entorhinal cortex, abnormal levels of cortical tau on PET are rarely found with Aβ below 40 CL. Above 40 CL prevalence of T+ accelerates in all areas. Moderate Aβ levels are required before abnormal neocortical tau becomes detectable.