Impact of Bevacizumab on Visual Function, Tumor Size, and Toxicity in Pediatric Progressive Optic Pathway Glioma: A Retrospective Nationwide Multicentre Study.
Carlien A M BennebroekJudith van ZwolGiorgio L PorroRianne OostenbrinkAnne T M DittrichAnnabel L W GrootJan W PottEtienne J M JanssenNoël J BauerMaria M van GenderenPeerooz SaeedMaarten H LequinPim de GraafAntoinette Y N Schouten-van MeeterenPublished in: Cancers (2022)
Treatment of BVZ in pediatric patients with OPG revealed stabilisation in the majority of patients, but was followed by progression at a later time point in more than 60% of patients. This profile seems relatively acceptable given the benefits of visual field improvement in more than 70% of analysed eyes and visual acuity improvement in more than 20% of eyes at the cessation of BVZ.