IL-2 modulates Th2 cell responses to glucocorticosteroid: A cause of persistent type 2 inflammation?

Tharsan KanagalingamLauren SolomonMeerah VijeyakumaranNami Shrestha PalikheHarissios VliagoftisLisa Cameron

Published in: Immunity, inflammation and disease (2019)

IL-2 downregulates Th2 cell responses to GC, supporting both their survival and pro-inflammatory capacity. These results suggest that a patient's potential to produce IL-2 may be a determinant in asthma severity.

Keyphrases

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