Intra- and extracellular real-time analysis of perfused fibroblasts using an NMR bioreactor: A pilot study.
Christian UrzìChristoph MeyerDéborah MathisPeter VermathenJean-Marc NuofferPublished in: Journal of inherited metabolic disease (2024)
Discrimination of intra- and extracellular metabolic contributions helps understanding the underlying mechanisms of mitochondrial disorders, uncovers potential metabolic biomarkers, and unravels metabolic pathway-specific adaptations in response to metabolic perturbations.