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The in vivo transcriptome of Schistosoma mansoni in the prominent vector species Biomphalaria pfeifferi with supporting observations from Biomphalaria glabrata.

Sarah K BuddenborgBishoy KamelBen HaneltLijing BuSi-Ming ZhangGerald M MkojiEric S Loker
Published in: PLoS neglected tropical diseases (2019)
This in vivo study, emphasizing field-derived snails and schistosomes, but supplemented with observations from a lab model, provides a distinct view from previous studies of development of cultured intramolluscan stages from lab-maintained organisms. We found many highly represented transcripts with suspected or unknown functions, with connection to intramolluscan development yet to be elucidated.
Keyphrases
  • gene expression
  • endothelial cells
  • pulmonary embolism
  • genome wide
  • dna methylation
  • gram negative
  • case control