Ex vivo and in vivo T cell-depleted allogeneic stem cell transplantation in patients with acute myeloid leukemia in first complete remission resulted in similar overall survival: on behalf of the ALWP of the EBMT and the MSKCC.
Florent MalardMyriam LabopinChristina ChoDidier BlaiseEsperanza B PapadopoulosJakob PasswegRichard O'ReillyEdouard ForcadeMolly MaloyLiisa VolinHugo Castro-MalaspinaYosr HicheriAnn A JakubowskiCorentin OrvainSergio GiraltMohamad MohtyArnon NaglerMiguel-Angel PeralesPublished in: Journal of hematology & oncology (2018)
These data suggest that both ex vivo CD34-selected and in vivo ATG T cell depletion are associated with a rather high OS and should be compared in a prospective randomized trial.