Correlation between biofilm formation and resistance toward different commonly used antibiotics along with extended spectrum beta lactamase production in uropathogenic Escherichia coli isolated from the patients suspected of urinary tract infections visiting Shree Birendra Hospital, Chhauni, Kathmandu, Nepal.
Sanjeev NeupaneNarayan Dutt PantSaroj KhatiwadaRaina ChaudharyMegha Raj BanjaraPublished in: Antimicrobial resistance and infection control (2016)
The ability of biofilm formation was found to be significantly higher in ESBL producing strains of E. coli than that in ESBL non producing strains (p < 0.05). There was higher resistance rate to antimicrobial agents among biofilm producing strains of E. coli than that in biofilm non producing strains. According to our antimicrobial susceptibility pattern for E. coli, to start preliminary treatment for UTI in Nepal, we recommend to use amikacin or nitrofurantoin. Further, for the treatment of the UTI, the antibiotics should be selected on the basis of the urine culture and sensitivity report.
Keyphrases
- escherichia coli
- biofilm formation
- urinary tract infection
- staphylococcus aureus
- klebsiella pneumoniae
- pseudomonas aeruginosa
- end stage renal disease
- chronic kidney disease
- ejection fraction
- healthcare
- newly diagnosed
- emergency department
- tertiary care
- cystic fibrosis
- prognostic factors
- multidrug resistant
- smoking cessation