Lewis and ABO histo-blood types and the secretor status of patients hospitalized with COVID-19 implicate a role for ABO antibodies in susceptibility to infection with SARS-CoV-2.

Eva Maria MatzholdAndrea BergholdMaria Karin Berta BemelmansChiara BanfiEvelyn StelzlHarald Hans KesslerIvo SteinmetzRobert KrauseHerbert WurzerPeter SchlenkeThomas Wagner

Published in: Transfusion (2021)

Blood types Lewis (a-b-) and O were found to be protective factors, whereas the group AB is suggested to be a risk factor for COVID-19. The antigens investigated may not be prognostic for disease severity, but a role for ABO isoagglutinins in SARS-CoV-2 infections is strongly suggested.

Keyphrases

sars cov
respiratory syndrome coronavirus
end stage renal disease
coronavirus disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
dendritic cells
patient reported outcomes