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Evaluation of prescribing patterns of switching to and add-on lemborexant in patients treated with hypnotic medication: a nationwide claims database study in Japan.

Sachiko Tanaka-MizunoKenichi FujimotoKazuo MishimaYukinori SakataToshiki FukasawaKayoko MizunoSatomi YoshidaMika IshiiTakehiro TaninagaNaoki KubotaMargaret MolineKoji Kawakami
Published in: Expert opinion on pharmacotherapy (2024)
The proportion of successful switching was higher in patients who switched to lemborexant than in those who added lemborexant as a concomitant treatment. The lower success proportion in the add-on cohort might be related to clinically more severe insomnia, and/or a concomitant prescription of benzodiazepine or non-benzodiazepine, from which discontinuation may be challenging.
Keyphrases
  • adverse drug
  • primary care
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  • drug induced
  • sleep quality
  • physical activity
  • depressive symptoms
  • combination therapy
  • electronic health record