Sertoli cell-conditioned medium can improve blood-testis-barrier function and spermatogenesis in azoospermia mice induced by scrotal hyperthermia: An experimental study.

Fakhroddin AghajanpourReza SoltaniAzar AfsharHojjat-Allah AbbaszadehFatemeh Fadaei FathabadiNafiseh MoeinianAbbas AliaghaeiAli Dehghani NejadReza Mastery FarahaniMohsen Norouzian Mohammad-Amin Abdollhifar

Published in: International journal of reproductive biomedicine (2024)

Findings suggest that growth factors of SCCM stimulate the proliferation and differentiation of germ cells through paracrine effects and upregulate the blood-testis-barrier-associated genes in mice subjected to scrotal hyperthermia.

Keyphrases

high fat diet induced
induced apoptosis
signaling pathway
single cell
cell cycle arrest
cell therapy
genome wide
gene expression
wild type
oxidative stress
cell proliferation
mesenchymal stem cells
dna methylation
cell death
transcription factor
adipose tissue