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Discovery of "folded DNA" structures in human cells: Potential drug targets.

Robert B RaffaJoseph V PergolizziRobert TaylorMichael H Ossipovnull null
Published in: Journal of clinical pharmacy and therapeutics (2018)
The newly identified "folded DNA" structures ("I-motifs" and "G-quadruplexes") could represent novel drug-discovery targets, most likely for cancer.
Keyphrases
  • drug discovery
  • circulating tumor
  • cell free
  • single molecule
  • high resolution
  • papillary thyroid
  • small molecule
  • squamous cell
  • nucleic acid
  • human health
  • adverse drug