Toward Model-Based Informed Precision Dosing of Vancomycin in Hematologic Cancer Patients: A First Step.
Jessica Le BlancDenis ProjeanSandra SavignacSophie LéveilléMarie-Pier DucasAnnie Brisebois-BoyerAmélie MarsotPublished in: Clinical pharmacokinetics (2023)
To our knowledge, this study provides the first model-informed AUC-based strategy in North American hematologic cancer patients with or without HSCT. The resulting nomogram generated provides a simplified approach to improving the accuracy of initial vancomycin dosing in this population.