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Recent Progress in Lab-On-a-Chip Systems for the Monitoring of Metabolites for Mammalian and Microbial Cell Research.

Esma DervisevicKellie L TuckNicolas H VoelckerVictor J Cadarso
Published in: Sensors (Basel, Switzerland) (2019)
Lab-on-a-chip sensing technologies have changed how cell biology research is conducted. This review summarises the progress in the lab-on-a-chip devices implemented for the detection of cellular metabolites. The review is divided into two subsections according to the methods used for the metabolite detection. Each section includes a table which summarises the relevant literature and also elaborates the advantages of, and the challenges faced with that particular method. The review continues with a section discussing the achievements attained due to using lab-on-a-chip devices within the specific context. Finally, a concluding section summarises what is to be resolved and discusses the future perspectives.
Keyphrases
  • high throughput
  • circulating tumor cells
  • single cell
  • cell therapy
  • systematic review
  • loop mediated isothermal amplification
  • microbial community
  • real time pcr
  • mesenchymal stem cells