Increased IgE Deposition in Appendicular Tissue Specimens Is Compatible with a Type I Hypersensitivity Reaction in Acute Appendicitis.
Nuno CarvalhoAndré Boler Cláudio da Silva BarrosHélder Oliveira CoelhoAna CóiasPedro BotelhoBrigitta CismasiuLuis Ferreira MoitaPaulo Matos da CostaPublished in: Mediators of inflammation (2021)
In this study, phlegmonous appendicitis had the highest number of IgE-positive appendicular cells. These findings suggest that an allergic reaction can contribute to the pathophysiology of AA, opening a novel possibility for preventive measures in a disease that typically requires surgery.