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Genetically engineered E. coli invade epithelial cells and transfer their genetic cargo into the cells: an approach to a gene delivery system.

Maryam ZareAli FarhadiFarahnaz ZareGholamreza Rafiei DehbidiFarzaneh ZarghampoorMohammad Karimi Baba AhmadiAbbas Behzad Behbahani
Published in: Biotechnology letters (2023)
This study shows that genetically engineered E. coli can enter cells, transport cargo into cells, and induce gene expression in the target cell. In addition, flow cytometry shows that the gene transfer efficiency was sufficient for protein expression.
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