Carotid artery molecular calcification assessed by [18F]fluoride PET/CT: correlation with cardiovascular and thromboembolic risk factors.
Simon A CastroDaniele MuserHwan LeeEmily C HancinAustin J BorjaOswaldo AcostaThomas J WernerAnders ThomassenCaius ConstantinescuPoul Flemming Høilund-CarlsenAbass AlaviPublished in: European radiology (2021)
• Sodium fluoride ([18F]fluoride) PET/CT imaging identifies patients with early-stage atherosclerosis. • Carotid [18F]fluoride uptake is significantly higher in patients with increased risk of cardiovascular and thromboembolic events and inversely correlated with the level of physical activity. • Early detection of arterial mineralization at a molecular level could help guide clinical decisions in the context of cardiovascular risk assessment.
Keyphrases
- pet ct
- drinking water
- early stage
- risk assessment
- risk factors
- physical activity
- positron emission tomography
- atrial fibrillation
- cardiovascular disease
- body mass index
- chronic kidney disease
- single molecule
- genome wide
- squamous cell carcinoma
- human health
- gene expression
- photodynamic therapy
- depressive symptoms
- mass spectrometry