Inactivation of AMPK Leads to Attenuation of Antigen Presentation and Immune Evasion in Lung Adenocarcinoma.
Yajing GaoPekka PaivinenSushil TripathiEva Domènech-MorenoIris P L WongKari VaahtomeriAshwini S NagarajSarang S TalwelkarMarc ForetzEmmy W VerschurenBenoit ViolletYan YanTomi P MäkeläPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
The results provide evidence that the immune evasion noted in LKB1-inactivated lung cancer is due to subsequent inactivation of AMPK and attenuation of antigen presentation.
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