Liquid chromatography-quadrupole orbitrap and liquid chromatography-tandem mass spectrometry system for rapid identification and quantitation of thirty nonsteroidal anti-inflammatory drugs and acetaminophen in illegal products.
Hyoung-Joon ParkHyeon Joo HamYoon Ji YangMin Kyeong SeoHyung Il KimJi Hyun LeePublished in: Rapid communications in mass spectrometry : RCM (2023)
The developed analysis system, consisting of qualitative analysis using LC-Q-Orbitrap/MS and quantitative analysis using LC/MS/MS, can rapidly and accurately identify and quantify NSAIDs and acetaminophen while also identifying non-analytical components.
Keyphrases
- liquid chromatography
- liquid chromatography tandem mass spectrometry
- simultaneous determination
- mass spectrometry
- anti inflammatory drugs
- tandem mass spectrometry
- solid phase extraction
- high resolution mass spectrometry
- ultra high performance liquid chromatography
- high performance liquid chromatography
- high resolution
- gas chromatography
- ms ms
- liver injury
- systematic review