Relevance of Sex and Subtype in Patients With IBS: An Exploratory Study of Gene Expression.

Kristen R WeaverGail D'Eramo MelkusJason FletcherWendy A Henderson

Published in: Biological research for nursing (2020)

Diverse yet interconnected processes such as metabolism, inflammation, immunity, social behavior, and pain are associated with differences in gene expression between participants with IBS and HC. These findings lend support for genomic associations with the brain-gut connection in patients with IBS and highlight the relevance of sex and IBS subtype in performing such analyses.

Keyphrases

gene expression
irritable bowel syndrome
dna methylation
oxidative stress
chronic pain
mental health
pain management
white matter
neuropathic pain
genome wide
spinal cord