Sex differences in circulating proteins in heart failure with preserved ejection fraction.
Susan StienenJoão Pedro FerreiraMasatake KobayashiGregoire Preud'hommeDaniela DobreJean-Loup MachuKevin DuarteEmmanuel BressoMarie-Dominique DevignesNatalia López AndrésNicolas GirerdSvend AakhusGiuseppe AmbrosioHans-Peter Brunner-La RoccaRicardo Fontes-CarvalhoAlan G FraserLoek van HeerebeekGilles de KeulenaerPaolo MarinoKenneth McDonaldAlexandre MebazaaZoltàn PappRiccardo RaddinoCarsten TschöpeWalter J PaulusFaiez ZannadPatrick RossignolPublished in: Biology of sex differences (2020)
In chronic HFpEF, assessing sex differences in a wide range of circulating proteins led to the identification of 9 proteins that were differentially expressed between female and male patients. These findings may help further investigations into potential pathophysiological processes contributing to HFpEF.