The MIND diet, brain transcriptomic alterations, and dementia.
A Heather EliassenAna W CapuanoPuja AgarwalZoe ArvanitakisYanling WangPhilip L De JagerJulie A SchneiderShinya TasakiKatia de Paiva LopesFrank B HuDavid A BennettLiming LiangFrancine GrodsteinPublished in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)
Why healthy dietary patterns are associated with lower dementia risk are unknown. We integrated dietary, brain transcriptomic, and cognitive data in older adults. Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) diet intake is correlated with a specific brain transcriptomic profile. This brain transcriptomic profile score is associated with better cognitive health. More data are needed to elucidate the causality and functionality of identified genes.