Comparative effectiveness and safety of antiplatelet drugs in patients with diabetes mellitus and acute coronary syndrome.

Julia SpoendlinJoshua J GagneJennifer J LeweyElisabetta PatornoSebastian SchneeweissRishi J Desai

Published in: Pharmacoepidemiology and drug safety (2018)

Prasugrel was associated with superior cardiovascular outcomes and a higher risk of short-term bleeding compared to clopidogrel in patients with ACS and DM. Comparative outcomes were similar between ticagrelor and clopidogrel or prasugrel and ticagrelor.

Keyphrases

acute coronary syndrome
percutaneous coronary intervention
antiplatelet therapy
st segment elevation myocardial infarction
st elevation myocardial infarction
glycemic control
atrial fibrillation
coronary artery disease
metabolic syndrome
adipose tissue
insulin resistance