High production of pro-inflammatory cytokines by maternal blood mononuclear cells is associated with reduced maternal malaria but increased cord blood infection.

Carlota DobanoTamara BerthoudMaria Nelia ManacaAugusto NhabombaCaterina GuinovartRuth AguilarArnoldo BarbosaPenny GrovesMauricio H RodríguezAlfons JimenezLazaro M QuimiceJohn J AponteJaume OrdiDenise L DoolanAlfredo MayorPedro L Alonso

Published in: Malaria journal (2018)

Complex network of immuno-pathological cytokine mechanisms in the placental and utero environments showed a potential trade-off between positive and negative effects on mother and newborn susceptibility to infection.

Keyphrases

cord blood
induced apoptosis
birth weight
pregnancy outcomes
cell cycle arrest
peripheral blood
risk assessment
endoplasmic reticulum stress
signaling pathway
pregnant women
oxidative stress
cell proliferation
human health
gestational age
network analysis
weight gain
pi k akt