Targeting autophagy with tamoxifen in breast cancer: From molecular mechanisms to targeted therapy.

Mohammad Yassin ZamanianMaryam GolmohammadiAmir Nili-AhmadabadiAmeer A AlameriMohammed Al-HassanShadia Hamoud AlshahraniMohammed Sami HasanAndrés Alexis Ramírez-CoronelQutaiba A QasimMahsa HeidariAmita Verma

Published in: Fundamental & clinical pharmacology (2023)

Therefore, by overcoming endocrine resistance in estrogen receptor-positive breast tumors, autophagy inhibition may improve the therapeutic efficacy of TAM.

Keyphrases

estrogen receptor
cell death
endoplasmic reticulum stress
signaling pathway
oxidative stress