Role of Nrf2 in Lipopolysaccharide-Induced Acute Kidney Injury: Protection by Human Umbilical Cord Blood Mononuclear Cells.

Li-Xin FengFei ZhaoQian LiuJin-Cheng PengXiang-Jie DuanPing YanXi WuHong-Shen WangYin-Hao DengShao-Bin Duan

Published in: Oxidative medicine and cellular longevity (2020)

All results suggest that hUCBMNCs can protect against LPS-induced AKI via the Nrf2 pathway. Activating Nrf2 can upregulate autophagy to protect LPS-induced cell injury.

Keyphrases

lps induced
inflammatory response
lipopolysaccharide induced
acute kidney injury
oxidative stress
cord blood
induced apoptosis
signaling pathway
cardiac surgery
endoplasmic reticulum stress
cell death
cell cycle arrest
single cell
cell therapy
peripheral blood