Neutrophil extracellular traps induce intrahepatic thrombotic tendency and liver damage in cholestatic liver disease.
Muxin YuXiaowen LiLong XuChuwei ZhengWeiwei PanHui ChenXiaoyu LiuXianshan ZhangJinming ZhangPublished in: Hepatology communications (2024)
NETs promote intrahepatic activation of coagulation and inflammation, leading to liver tissue injury. Strategies targeting NET formation may offer a potential therapeutic approach for treating cholestatic liver disease.