Neural reactivity to affective stimuli and internalizing symptom dimensions in a transdiagnostic patient sample.

Maria Granros Annmarie MacNamara Heide KlumppK Luan PhanKatie L Burkhouse

Published in: Depression and anxiety (2022)

Results revealed a dissociable effect of IP symptom factors in a transdiagnostic sample such that enhanced reactivity to negative images was specific to enhanced fear-based anxiety symptoms while distress/misery symptoms predicted blunted affective reactivity. Neural affective reactivity may serve as an objective biological marker to elucidate the nature of psychological concerns in individuals with comorbid IPs.

Keyphrases

bipolar disorder
sleep quality
case report
single cell
convolutional neural network
depressive symptoms