AIMP1 promotes multiple myeloma malignancy through interacting with ANP32A to mediate histone H3 acetylation.

Rongfang WeiYan ZhuYuanjiao ZhangWene ZhaoXichao YuLing WangChunyan GuXiaosong GuYe Yang

Published in: Cancer communications (London, England) (2022)

Our data demonstrate that AIMP1 is a novel regulator of histone H3 acetylation interacting with ANP32A in MM, which accelerates MM malignancy via activation of the MAPK signaling pathway.

Keyphrases

signaling pathway
multiple myeloma
pi k akt
protein kinase
histone deacetylase
epithelial mesenchymal transition
electronic health record
induced apoptosis
transcription factor
big data
oxidative stress
cell proliferation
artificial intelligence