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Contribution of glutathione peroxidase 1 (Pro200Leu) single nucleotide polymorphism and serum homocysteine levels in the risk of acute myocardial infarction in Egyptians.

Lamia K IsmailMohamed F Abdel RahmanIngy M HashadSahar M Abdel-Maksoud
Published in: Journal, genetic engineering & biotechnology (2022)
The minor T allele of GPX1 Pro200Leu is not associated with AMI risk in this Egyptian population. However, high homocysteine serum levels might contribute independently to the risk of AMI. Finally, Hcy levels were not significantly different in homozygous minor TT compared to homozygous wild CC.
Keyphrases
  • acute myocardial infarction
  • percutaneous coronary intervention
  • left ventricular
  • anti inflammatory
  • heart failure
  • hydrogen peroxide
  • coronary artery disease
  • acute coronary syndrome
  • genetic diversity