Myelodysplastic Syndromes with Isolated 20q Deletion: A New Clinical-Biological Entity?
Alessia CampagnaDaniela De BenedittisLuana FianchiEmilia ScalzulliLorenzo RizzoPasquale NiscolaAnna Lina PiccioniAmbra Di VeroliStefano ManciniNicoletta VillivàTiziano MartiniSara MohamedIda CarmosinoMarianna CriscuoloSusanna FenuMaria Antonietta Aloe SpiritiFrancesco BuccisanoMarco ManciniAgostino TafuriMassimo BrecciaAntonella PoloniRoberto LatagliataPublished in: Journal of clinical medicine (2022)
According to our results, we hypothesize that MDSs with isolated del 20q may represent a distinct biological entity, with peculiar clinical and prognostic features. The physio-pathological mechanisms underlying the deletion of the chromosome 20 long arm are still unclear and warrant future molecular analysis.