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Adjuvant therapeutic potential of tonabersat in the standard treatment of glioblastoma: A preclinical F98 glioblastoma rat model study.

Valerie De MeulenaereEllen BonteJeroen VerhoevenJean-Pierre Kalala OkitoLeen PietersAnne VralOlivier De WeverLuc LeybaertIngeborg GoethalsChristian VanhoveBenedicte DescampsKarel Deblaere
Published in: PloS one (2019)
Our results demonstrate a therapeutic potential of tonabersat for the treatment of GB when used in combination with radiotherapy and temozolomide chemotherapy.
Keyphrases
  • early stage
  • locally advanced
  • radiation therapy
  • squamous cell carcinoma
  • stem cells
  • mesenchymal stem cells
  • radiation induced
  • replacement therapy
  • smoking cessation