Adjuvant therapeutic potential of tonabersat in the standard treatment of glioblastoma: A preclinical F98 glioblastoma rat model study.

Valerie De MeulenaereEllen BonteJeroen VerhoevenJean-Pierre Kalala OkitoLeen PietersAnne VralOlivier De WeverLuc LeybaertIngeborg GoethalsChristian VanhoveBenedicte DescampsKarel Deblaere

Published in: PloS one (2019)

Our results demonstrate a therapeutic potential of tonabersat for the treatment of GB when used in combination with radiotherapy and temozolomide chemotherapy.

Keyphrases

early stage
locally advanced
radiation therapy

squamous cell carcinoma
stem cells

mesenchymal stem cells
radiation induced

replacement therapy
smoking cessation