Serum dickkopf-3 is associated with death and vascular events after ischemic stroke: an observational study from CATIS.
Zhengbao ZhuDaoxia GuoChongke ZhongAili WangTan XuYanbo PengHao PengQunwei LiZhong JuDeqin GengJing ChenYonghong ZhangJiang HePublished in: Journal of neuroinflammation (2020)
Both low and high serum Dkk-3 levels are associated with increased risks of death and vascular events within 3 months after ischemic stroke, indicating that serum Dkk-3 may have a special effect on the prognosis of ischemic stroke. We also found that serum Dkk-3 might be a prognostic biomarker for ischemic stroke. Further studies are needed to replicate our findings and to determine the optimal levels of serum Dkk-3.