Cervicovaginal cytology, HPV testing and vaginal flora in transmasculine persons receiving testosterone.

Lawrence Hsu LinFang ZhouEsther ElishaevSamer KhaderAndrea HernandezAlan MarcusEsther Adler

Published in: Diagnostic cytopathology (2022)

Our study cohort demonstrated a high percentage of abnormal Pap tests in transmasculine persons receiving testosterone. Testosterone seems to induce changes in squamous cells and shifts in vaginal flora. HR-HPV testing can be a useful adjunct in the workup of abnormal Pap tests from transmasculine individuals.

Keyphrases

high grade
replacement therapy
low grade
induced apoptosis
cell cycle arrest
cervical cancer screening
cell death
signaling pathway
cell proliferation