Significance of Cytomegalovirus gB Genotypes in Adult Patients Undergoing Hematopoietic Stem Cell Transplantation: Insights from a Single-Centre Investigation.
Tamara VasiljevicMarko JankovićAna TomicIda BakracStefan RadenovicDanijela KaralicAleksandra KneževićTanja JovanovićIrena DjunicMilena Todorović BalintPublished in: Pharmaceuticals (Basel, Switzerland) (2024)
locus imparting both beneficial (earlier platelet engraftment, less frequent MRD post HSCT) and adverse effects (shorter overall survival, more frequent acute GvHD, less frequent 100% chimerism at day 90) to the transplanted host. Comprehensive molecular investigations are necessary to validate this apparent duality, as the potential benefits of CMV could perhaps be utilized for the benefit of the patient in the future.
Keyphrases
- patients undergoing
- allogeneic hematopoietic stem cell transplantation
- liver failure
- acute myeloid leukemia
- hematopoietic stem cell
- respiratory failure
- acute lymphoblastic leukemia
- single molecule
- young adults
- intensive care unit
- diffusion weighted imaging
- aortic dissection
- free survival
- childhood cancer
- extracorporeal membrane oxygenation