Transcriptional Profiling of Egg Allergy and Relationship to Disease Phenotype.

Roman KosoyCharuta AgasheAlexander GrishinDonald Y LeungRobert A WoodScott H SichererStacie M JonesA Wesley BurksWendy F DavidsonRobert W LindbladPeter DawsonMiriam MeradBrian A KiddJoel T DudleyHugh A SampsonMaria Cecilia Berin

Published in: PloS one (2016)

Transcriptional profiling identified several novel pathways and processes that differed when comparing the response to egg allergen in BET, BER, and AC groups. We conclude that this approach is a useful hypothesis-generating mechanism to identify novel immune processes associated with allergy and tolerance to forms of egg.

Keyphrases

gene expression
transcription factor
single cell
atopic dermatitis
oxidative stress
allergic rhinitis