Iron accumulation is associated with periodontal destruction in a mouse model of HFE-related haemochromatosis.
Pingping HanTianqing LiuCedryck VaquetteDavid FrazerGregory AndersonSašo IvanovskiPublished in: Journal of periodontal research (2021)
Our results suggest that the iron loading in a mouse model of HH decreases alveolar bone formation and leads to alterations in the inflammatory state in the periodontium. Periodontal health should be assessed during the clinical assessment of HFE-HH patients.