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Cardiac Localized Polycystin-2 in the Natriuretic Peptide Signaling Pathway and Hypertension.

Karla Marie Márquez-NoguerasBrandon ElliottPaula ThuoElisabeth DiNelloRyne M KnutilaGeena E FritzmannVirdjinija VuchkovskaSarah FluryMonte WillisArlene B ChapmanQuan CaoDavid Y BarefieldIvana Y Kuo
Published in: Journal of the American Society of Nephrology : JASN (2024)
Natriuretic peptide production required cardiac localized polycystin-2 and loss of this pathway may contribute to the development of hypertension in ADPKD.
Keyphrases
  • blood pressure
  • signaling pathway
  • left ventricular
  • pi k akt
  • epithelial mesenchymal transition
  • heart failure
  • induced apoptosis
  • atrial fibrillation
  • polycystic kidney disease