Cardiac Localized Polycystin-2 in the Natriuretic Peptide Signaling Pathway and Hypertension.
Karla Marie Márquez-NoguerasBrandon ElliottPaula ThuoElisabeth DiNelloRyne M KnutilaGeena E FritzmannVirdjinija VuchkovskaSarah FluryMonte WillisArlene B ChapmanQuan CaoDavid Y BarefieldIvana Y KuoPublished in: Journal of the American Society of Nephrology : JASN (2024)
Natriuretic peptide production required cardiac localized polycystin-2 and loss of this pathway may contribute to the development of hypertension in ADPKD.