Regulation of Salivary Peptidoglycan Recognition Protein 1 in Adolescents.
T RaivistoA M HeikkinenA SilbereisenL KovanenH RuokonenT TervahartialaJ HaukkaT SorsaNagihan BostanciPublished in: JDR clinical and translational research (2019)
PGLYRP1, a member of peptidoglycan recognition proteins, is a ligand for TREM-1. Elevated PGLYRP1 levels in adolescents with gingivitis and subclinical periodontitis and its positive correlation with TREM-1 and aMMP-8 may indicate an association of PGLYRP1 with initial stages of periodontal disease. However, it has a lower discriminating capacity and is therefore a less reliable marker alone in the diagnosis of periodontal disease in adolescents.