A SREBF2-dependent gene program drives an immunotolerant dendritic cell population during cancer progression.
Michael P PlebanekYue XueY-Van NguyenNicholas C DeVitoXueying WangAlisha HoltzhausenGeorgia M BeasleyNagendra YarlaBala ThievanthiranBrent A HanksPublished in: bioRxiv : the preprint server for biology (2023)
The metabolic transcription factor, SREBF2, regulates the development and tolerogenic function of the mregDC population within the tumor microenvironment.